Is Cold Agglutinin Disease triggered by cold weather?
While data show that levels such as hemoglobin may differ from season to season,* the burden of hospitalization and transfusion is consistent in CAD, regardless of season.1
Data from a retrospective review of a claims database (n=808).
*The medium minimum Hb value for winter compared with summer was decreased by 0.54 g/dL (P<0.001). The median maximum bilirubin and LDH increased by
Find out more about the risks of CAD here.