Is Cold Agglutinin Disease hereditary?
CAD is not a hereditary disease.1 CAD is a rare disease, and, to be accurately diagnosed, 3 main criteria must be met2-4:
- 1. Evidence of hemolysis.
- 2. Positive Coombs test results (direct antibody test) for C3d.
- 3. Presence of Cold Agglutinin Titer ≥1:64.
Unlike CAS, CAD is not secondary to cancer or an acute infection.
Find out more about the diagnosis of CAD here.